ENDOVASCULAR EMBOLIZATION FOR PEDIATRIC CEREBRAL ARTERIOVENOUS MALFORMATIONS

Arteriovenous malformations (AVMs) of the central nervous system (CNS) have a higher rupture rate and are a major cause of spontaneous intracranial hemorrhage in children compared to adults.Computed tomography angiography (CTA) is the gold standard diagnostic tool, and surgical excision remains the gold standard therapy, which can be used as an alt

Abstract Background Clear cell renal cell cancer (ccRCC), the 8th leading cause of cancer-related death in the US, is challenging to treat due to high level intratumoral heterogeneity (ITH) and the paucity of druggable driver mutations.CcRCC is unusual for its high frequency of epigenetic regulator mutations, such as the SETD2 histone H3 lysine 36